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  • A Deep Dive on Calcium Signaling

    Posted | by Marah Natural Admin

    A Deep Dive on Calcium Signaling

    Calcium (Ca2+) ions are the main communication signal between the cells. Found in the intracellular and external fluids, they play a key role in cell signal transmission after entering the cytoplasm—featuring the effect of allosteric regulatory proteins on various enzymes and proteins in the body.

     The second signal transmission resulting from activated ion or indirect signal transmission channels (i.e., G protein-coupled receptors) helps to transmit information between the cells and facilitate the gene transfer effect. That said, research has found that calcium ions’ intracellular concentration is generally about 100 nM, which is...


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  • Calcium Absorption and Homeostasis: Understanding the Complexity

    Posted | by Marah Natural Admin

    Calcium Absorption and Homeostasis: Understanding the Complexity

    The bones are our largest reservoirs of calcium, containing about 99% of the calcium found in the body. Calcium—in the form of calcium hydroxyapatite (Ca₁₀(PO₄)₆(OH)₂)—is also found in the teeth, in the circulatory system, in the muscles, and in other tissues. But how much do we really know about the stuff?

    Calcium plays a crucial role in the body. The vital mineral helps to regulate the blood vessels, oversees our hormone production, and is key to our intracellular signaling—or the way the cells communicate. It’s also involved in our muscle...


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  • Calcium-mechanisms of Regulation and Absorption in the Body

    Posted | by Marah Natural Admin

    Calcium-mechanisms of Regulation and Absorption in the Body

    Our bones are the largest reservoirs of calcium, harboring most of the calcium in our bodies (about 99%) in the form of calcium hydroxyapatite. Calcium is also found in teeth, the circulatory system, extracellular fluid, muscles and other tissues. It plays crucial roles such as regulating the tone of the blood vessels, production of hormones, intracellular signaling (communication of information within body cells), muscle contraction, nerve communication, among other functions.

    Because of this critical role played by calcium, its normal blood concentration is tightly controlled by the body to a level of...


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  • Diabetes: A metabolic disorder that impacts growth and daily energy

    Posted | by Marah Natural Admin

    Diabetes: A metabolic disorder that impacts growth and daily energy

    Diabetes is often referred to as the silent killer, and we want to highlight how diabetes can impact your health. Diabetes impact approximately 10% of Americans and Canadians, and studies show that the numbers are growing at an alarming rate. It is estimated that one in three U.S. children born in the year 2000 and onward will develop diabetes.

    So what can we do to ensure that our future generations are safe from this chronic health condition? Please keep reading to learn about what diabetes is, how it occurs in the body, who is affected by it,...


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  • Osteoporosis: A Disease that Shatters Promising Futures

    Posted | by Marah Natural Admin

    Osteoporosis: A Disease that Shatters Promising Futures

    As we age, we come to understand more than ever the value of looking after our health. We recognize that a healthy body and mind can often lead to a better overall lifestyle and wellbeing. What’s not often discussed, however, is how our bone density diminishes over time— a critical factor that determines our overall health and wellness.

    This month, we are recognizing World Osteoporosis Day. We want to raise the awareness of osteoporosis, a disease that impacts the lives of 14 million Americans and Canadians, with additionally 44 million Americans at increased risk of developing this “silent disease” over...


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