Kanchana. N1, Saikumar. P2 1-Department of physiology / Sree Balaji Medical College, Bharath University, Chennai India / Second year Physiology PG 2- Department of physiology / Sree Balaji Medical College, Bharath University, Chennai India / Professor and HOD

Abstract:

Introduction: Hyperglycemia in Diabetes Mellitus is known to have its effect on almost all body system through alterations in structural and biochemical changes in tissues.From this study, it is hypothesized that alteration in calcium flux may adversely affect the insulin secretion as it is a calcium-dependent process.

Aim And Objectives: This study was done to estimate the serum calcium levels in type 2 Diabetes mellitus.

Objectives:

  1. Estimation of blood glucose levels in all subjects.
  2. Estimation of serum calcium levels in diabetes and non-diabetes.
  3. Compare the serum calcium levels in diabetes and non-diabetes.

Materials and methods:

Case control study.

Study Design: Diabetes subjects (cases) n=50 Age and sex matched

Diabetes subjects (cases) n=50 Age and sex matched

Age and sex matched non diabetes (controls) n=50

Plasma glucose levels was estimated by GOD-POD method.Serum calcium level was estimated by calcium Arsenazo method for all subjects at central lab of SBMCH,Chennai.

Results And Conclusion: Results were analyzed using anova single factor.f statistical was greater than f critical value.

A negative correlation was observed between serum calcium levels and plasma blood glucose levels. Also the p value was found to be less than 0.05 which confirmed that correlation was statistically significant.


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